\u0130lk kez 19. y\u00fczy\u0131lda t\u0131p uzmanlar\u0131nca geli\u015ftirilen sakinle\u015ftirici ila\u00e7lar\u0131n (trankilizan) hepsi, potasyum bromid esasl\u0131d\u0131r. Yan etki olarak, a\u015f\u0131r\u0131 t\u00fck\u00fcr\u00fck \u00fcretimine neden olduklar\u0131ndan, bunlar pek tutulmad\u0131. 1903’te Almanya’ da Veronal ad\u0131 verilen barbit\u00fcrat esasl\u0131 uyku ilac\u0131 bulundu.<\/p>\n
Daha sonra barbit\u00fcrat bile\u015fikleri, sakinle\u015ftirici olarak kullan\u0131lmaya ba\u015fland\u0131. Halen en geni\u015f bi\u00e7imde kullan\u0131lan sakinle\u015ftiriciler, benzodiazepin esasl\u0131 olanlard\u0131r.<\/p>\n
Bunlar\u0131n en bilinenleri aras\u0131nda, Valium, Librium ve Mogadon say\u0131labilir. Barbit\u00fcrat esasl\u0131 ila\u00e7lara g\u00f6re daha az yan etkileri g\u00f6r\u00fclen bu ila\u00e7lar, 1950’li y\u0131llarda \u0130sve\u00e7li ila\u00e7 firmas\u0131 Hofmann La Roche taraf\u0131ndan \u00fcretildi.<\/p>\n
Sakinle\u015ftirici<\/b> veya sedatif<\/b>, d\u00fc\u015f\u00fck dozda kullan\u0131ld\u0131\u011f\u0131nda gerginlik ve bunalt\u0131y\u0131 (anksiyete) gideren, duygu ve davran\u0131\u015flarda yat\u0131\u015ft\u0131r\u0131c\u0131 etki sa\u011flayan, y\u00fcksek dozda ise bilin\u00e7 bulan\u0131kl\u0131\u011f\u0131 ve uyku veren ila\u00e7lar\u0131n genel ad\u0131d\u0131r. Merkez\u00ee sinir sisteminin \u00e7al\u0131\u015fmas\u0131n\u0131 yava\u015flat\u0131r. Farmakolojik olarak uygun dozda kullan\u0131ld\u0131\u011f\u0131 zaman uyku sa\u011flar. Sedatif etki hipnotik etkiden daha zay\u0131ft\u0131r. Kullanana uyku vermez. Sadece sakinle\u015ftirir. Bir\u00e7ok sedatif ila\u00e7 y\u00fcksek dozda anestezik etki g\u00f6sterir.<\/p>\n","protected":false},"excerpt":{"rendered":"
\u0130lk kez 19. y\u00fczy\u0131lda t\u0131p uzmanlar\u0131nca geli\u015ftirilen sakinle\u015ftirici ila\u00e7lar\u0131n (trankilizan) hepsi, potasyum bromid esasl\u0131d\u0131r. Yan etki olarak, a\u015f\u0131r\u0131 t\u00fck\u00fcr\u00fck \u00fcretimine neden olduklar\u0131ndan, bunlar pek tutulmad\u0131. 1903’te Almanya’ da Veronal ad\u0131…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[18],"tags":[772,774,771,773],"class_list":["post-1464","post","type-post","status-publish","format-standard","hentry","category-saglik","tag-sakinlestirici","tag-sakinlestirici-ilac","tag-sakinlestirici-ilaci-kim-buldu","tag-sakinlestirici-ilaclar"],"_links":{"self":[{"href":"https:\/\/www.ilkkimbuldu.com\/index.php?rest_route=\/wp\/v2\/posts\/1464"}],"collection":[{"href":"https:\/\/www.ilkkimbuldu.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ilkkimbuldu.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ilkkimbuldu.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ilkkimbuldu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1464"}],"version-history":[{"count":5,"href":"https:\/\/www.ilkkimbuldu.com\/index.php?rest_route=\/wp\/v2\/posts\/1464\/revisions"}],"predecessor-version":[{"id":7603,"href":"https:\/\/www.ilkkimbuldu.com\/index.php?rest_route=\/wp\/v2\/posts\/1464\/revisions\/7603"}],"wp:attachment":[{"href":"https:\/\/www.ilkkimbuldu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1464"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ilkkimbuldu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1464"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ilkkimbuldu.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1464"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}