{"id":319,"date":"2011-12-24T16:33:45","date_gmt":"2011-12-24T14:33:45","guid":{"rendered":"http:\/\/www.ilkkimbuldu.com\/?p=319"},"modified":"2019-07-30T15:14:05","modified_gmt":"2019-07-30T13:14:05","slug":"aspirini-kim-buldu","status":"publish","type":"post","link":"https:\/\/www.ilkkimbuldu.com\/?p=319","title":{"rendered":"Aspirini kim buldu"},"content":{"rendered":"

Aspirin<\/strong>, Asetilsalisilik asit (ASA) olarak da bilinen aspirin, a\u011fr\u0131, ate\u015f ve iltihap tedavisinde kullan\u0131lan bir ila\u00e7t\u0131r. Kullan\u0131ld\u0131\u011f\u0131 spesifik enflamatuvar durumlar aras\u0131nda Kawasaki hastal\u0131\u011f\u0131, perikardit ve romatizmal ate\u015f bulunur. Kalp krizinden k\u0131sa bir s\u00fcre sonra verilen aspirin \u00f6l\u00fcm riskini azalt\u0131r. Aspirin, y\u00fcksek risk alt\u0131ndaki insanlarda kalp krizi, inme ve kan p\u0131ht\u0131lar\u0131n\u0131 \u00f6nlemeye yard\u0131mc\u0131 olmak i\u00e7in uzun vadede kullan\u0131l\u0131r.<\/p>\n

Aspirinin kimyasal ad\u0131 olan “asetilsalisilik asit”, ilk kez 1853 y\u0131l\u0131nda Alsasl\u0131 kimyac\u0131 Charles Fr\u00e9d\u00e9ric Gerhardt<\/strong> taraf\u0131ndan sentetik olarak elde edilmi\u015fti. Asetilsalisilik asitin t\u0131bbi \u00f6zellikleri ise 1895’da Heinrich Dresser<\/strong> taraf\u0131ndan ke\u015ffedildi.<\/p>\n

1897 y\u0131l\u0131nda ise Bayer firmas\u0131ndan Dr. Felix Hoffman<\/strong>, bu maddeyi tedavi amac\u0131yla a\u011f\u0131zdan al\u0131nabilecek kadar kat\u0131\u015f\u0131ks\u0131z bir bi\u00e7imde \u00fcretmeyi ba\u015fard\u0131, \u00d6nceleri, yaln\u0131zca Almanya’da re\u00e7ete kar\u015f\u0131l\u0131\u011f\u0131nda sat\u0131l\u0131yordu. 1915 y\u0131l\u0131ndan itibaren Bayer taraf\u0131ndan 20’l\u0131k paketler halinde tablet olarak piyasaya s\u00fcr\u00fcld\u00fc.<\/p>\n

G\u00fcn\u00fcm\u00fczde, re\u00e7etesiz sat\u0131lan aspirinin her t\u00fcrl\u00fc a\u011fr\u0131ya kar\u015f\u0131 kullan\u0131m\u0131 halk aras\u0131nda \u00e7ok yayg\u0131nd\u0131r. K\u00fc\u00e7\u00fck rahats\u0131zl\u0131klar\u0131n tedavisinde olduk\u00e7a s\u0131k bir bi\u00e7imde t\u00fcketilen Aspirin, ilk kez 1899 y\u0131l\u0131 May\u0131s ay\u0131nda, Almanya’n\u0131n Leverkusen kentinde, Bayer AG firmas\u0131 taraf\u0131ndan toz halinde piyasaya s\u00fcr\u00fcld\u00fc.\u00a0Bayer, ilac\u0131n ad\u0131n\u0131 Aspirin olarak vermi\u015f ve onu d\u00fcnya \u00e7ap\u0131nda satmaya ba\u015flam\u0131\u015ft\u0131r.<\/p>\n

Salisilik asit, bir cins s\u00f6\u011f\u00fct a\u011fac\u0131n\u0131n bitki \u00f6z\u00fcnde, keklik \u00fcz\u00fcm\u00fc ya\u011f\u0131nda, ke\u00e7isakal\u0131 bitkisinin (Spiraea ulmaria) \u00e7i\u00e7eklerinde tabii halde bulunur. Salisilik asidin asetil t\u00fcrevine (kimyasal olarak form\u00fcl\u00fcne asetil k\u00f6k\u00fc getirilmi\u015f olan\u0131na) aspirin denildi.<\/p>\n

Aspirin, her y\u0131l yakla\u015f\u0131k 40.000 ton (50 ila 120 milyar hap) t\u00fcketimin oldu\u011fu k\u00fcresel olarak en yayg\u0131n kullan\u0131lan ila\u00e7lardan biridir. Bir sa\u011fl\u0131k sisteminde ihtiya\u00e7 duyulan en etkin ve g\u00fcvenli ila\u00e7lar kategorisinde ve D\u00fcnya Sa\u011fl\u0131k \u00d6rg\u00fct\u00fc Temel \u0130la\u00e7 Listesinde yer almaktad\u0131r.<\/p>\n

Aspirin, ibuprofen veya naproksen allerjisi olan, salisilat intolerans\u0131 olan veya NSA\u0130\u0130’lere daha genel bir ila\u00e7 intolerans\u0131 olan ki\u015filer taraf\u0131ndan al\u0131nmamal\u0131 ve ast\u0131ml\u0131larda dikkatli olunmal\u0131d\u0131r.\u00a0\u00dcreticiler, mide astar\u0131na olan etkisi nedeniyle, peptik \u00fclser, hafif diyabet<\/a> veya gastrit hastalar\u0131na aspirin kullanmadan \u00f6nce doktora ba\u015fvurmalar\u0131n\u0131 \u00f6nerir.\u00a0Bu ko\u015fullardan hi\u00e7biri olmasa bile, aspirin alkol <\/a>veya varfarin ile al\u0131nd\u0131\u011f\u0131nda mide kanamas\u0131 riski hala artmaktad\u0131r.<\/p>\n","protected":false},"excerpt":{"rendered":"

Aspirin, Asetilsalisilik asit (ASA) olarak da bilinen aspirin, a\u011fr\u0131, ate\u015f ve iltihap tedavisinde kullan\u0131lan bir ila\u00e7t\u0131r. Kullan\u0131ld\u0131\u011f\u0131 spesifik enflamatuvar durumlar aras\u0131nda Kawasaki hastal\u0131\u011f\u0131, perikardit ve romatizmal ate\u015f bulunur. Kalp krizinden…<\/p>\n","protected":false},"author":1,"featured_media":8504,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[18],"tags":[1905,232,1904,1906,1903,1175,1177],"class_list":["post-319","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saglik","tag-asetilsalisilik-asit","tag-aspirin","tag-bayer","tag-carl-gerhardt","tag-felix-hoffman","tag-hap","tag-ilac"],"_links":{"self":[{"href":"https:\/\/www.ilkkimbuldu.com\/index.php?rest_route=\/wp\/v2\/posts\/319"}],"collection":[{"href":"https:\/\/www.ilkkimbuldu.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ilkkimbuldu.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ilkkimbuldu.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ilkkimbuldu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=319"}],"version-history":[{"count":9,"href":"https:\/\/www.ilkkimbuldu.com\/index.php?rest_route=\/wp\/v2\/posts\/319\/revisions"}],"predecessor-version":[{"id":17109,"href":"https:\/\/www.ilkkimbuldu.com\/index.php?rest_route=\/wp\/v2\/posts\/319\/revisions\/17109"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.ilkkimbuldu.com\/index.php?rest_route=\/wp\/v2\/media\/8504"}],"wp:attachment":[{"href":"https:\/\/www.ilkkimbuldu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=319"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ilkkimbuldu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=319"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ilkkimbuldu.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=319"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}